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Gene: Slc3a2 (solute carrier family 3 member 2) Rattus norvegicus
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Symbol: Slc3a2
Name: solute carrier family 3 member 2
Description: Exhibits neutral amino acid transmembrane transporter activity. Involved in L-leucine import across plasma membrane. Predicted to localize to several cellular components, including the cytosol; nucleus; and plasma membrane. Orthologous to human SLC3A2 (solute carrier family 3 member 2); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4F2 cell-surface antigen heavy chain; 4F2hc; antigen identified by monoclonal antibodies 4F2; Mdu1; solute carrier family 3 (activators of dibasic and neutral amino acid transport) member 2; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3, member 2
Orthologs:
Homo sapiens (human) : SLC3A2 (solute carrier family 3 member 2)  HGNC  Alliance
Mus musculus (house mouse) : Slc3a2 (solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc3a2 (solute carrier family 3 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC3A2 (solute carrier family 3 member 2)
Canis lupus familiaris (dog) : SLC3A2 (solute carrier family 3 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc3a2 (solute carrier family 3 member 2)
Sus scrofa (pig) : SLC3A2 (solute carrier family 3 member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01224,906,566 - 224,921,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01231,843,822 - 231,858,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,375,889 - 211,390,313 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,534,318 - 211,548,743 (-)NCBI
Celera1203,117,365 - 203,131,828 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc3a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3073
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.