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Gene: Mitf (melanocyte inducing transcription factor) Rattus norvegicus
Symbol: Mitf
Name: melanocyte inducing transcription factor
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and protein dimerization activity. Involved in transcription, DNA-templated. Predicted to localize to nucleus and protein-containing complex. Human ortholog(s) of this gene implicated in Tietz syndrome; Tietze's syndrome; Waardenburg syndrome type 2A; Waardenburg's syndrome; and familial melanoma. Orthologous to human MITF (melanocyte inducing transcription factor); PARTICIPATES IN interleukin-6 signaling pathway; melanoma pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: melanogenesis associated transcription factor; microphthalmia-associated transcription factor
Homo sapiens (human) : MITF (melanocyte inducing transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Mitf (melanogenesis associated transcription factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mitf (melanocyte inducing transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MITF (melanocyte inducing transcription factor)
Canis lupus familiaris (dog) : MITF (melanocyte inducing transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mitf (melanocyte inducing transcription factor)
Sus scrofa (pig) : MITF (melanocyte inducing transcription factor)
Chlorocebus sabaeus (African green monkey) : MITF (melanocyte inducing transcription factor)
Heterocephalus glaber (naked mole-rat) : Mitf (melanocyte inducing transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04130,172,484 - 130,425,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4130,172,727 - 130,425,532 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,667,943 - 194,921,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44132,534,187 - 132,745,669 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,971,000 - 132,989,691 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mitf
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3092
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.