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Gene: Mpz (myelin protein zero) Rattus norvegicus
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Symbol: Mpz
Name: myelin protein zero
Description: Involved in negative regulation of apoptotic process. Localizes to the basolateral plasma membrane; lysosome; and rough endoplasmic reticulum. Biomarker of diabetic neuropathy and sciatic neuropathy. Human ortholog(s) of this gene implicated in neuromuscular disease (multiple). Orthologous to human MPZ (myelin protein zero); INTERACTS WITH (20R)-20-hydroxypregn-4-en-3-one; (20S)-20-hydroxypregn-4-en-3-one; 3alpha-hydroxy-5beta-pregnan-20-one.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MPP; myelin peripheral protein; myelin protein P0; Myelin protein zero (Charcot-Marie-Tooth neuropathy 1B); P0
Orthologs:
Homo sapiens (human) : MPZ (myelin protein zero)  HGNC  Alliance
Mus musculus (house mouse) : Mpz (myelin protein zero)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpz (myelin protein zero)
Pan paniscus (bonobo/pygmy chimpanzee) : MPZ (myelin protein zero)
Canis lupus familiaris (dog) : MPZ (myelin protein zero)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpz (myelin protein zero)
Sus scrofa (pig) : MPZ (myelin protein zero)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01389,524,204 - 89,530,070 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,151,850 - 94,156,749 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,040,479 - 87,045,378 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,229,362 - 87,234,262 (+)NCBI
Celera1383,202,202 - 83,207,991 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mpz
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3109
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.