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Gene: Muc2 (mucin 2, oligomeric mucus/gel-forming) Rattus norvegicus
Symbol: Muc2
Name: mucin 2, oligomeric mucus/gel-forming
Description: Exhibits identical protein binding activity. Involved in several processes, including cellular response to tumor necrosis factor; response to lipopolysaccharide; and response to vitamin A. Localizes to cytoplasm; mucus layer; and nucleus. Used to study colitis; intestinal disease; and pneumonia. Biomarker of several diseases, including colitis (multiple); cystic fibrosis; liver cirrhosis; mucositis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in asthma. Orthologous to human MUC2 (mucin 2, oligomeric mucus/gel-forming); PARTICIPATES IN Entamoebiasis pathway; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; bisphenol A; chlorpyrifos.
Type: protein-coding
RefSeq Status: MODEL
Also known as: HH-Muc; intestinal mucin-2; LOC682800; LOC682824; LOW QUALITY PROTEIN: mucin-2; MLP; MUC-2; mucin 2; mucin-2; similar to Intestinal mucin-like protein (MLP)
Homo sapiens (human) : MUC2 (mucin 2, oligomeric mucus/gel-forming)  HGNC  Alliance
Mus musculus (house mouse) : Muc2 (mucin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Canis lupus familiaris (dog) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
Sus scrofa (pig) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Chlorocebus sabaeus (African green monkey) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Heterocephalus glaber (naked mole-rat) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01214,663,929 - 214,693,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01221,581,822 - 221,611,451 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1194,458,772 - 194,461,359 (+)NCBICelera
Celera1194,430,946 - 194,458,668 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Muc2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3123
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.