Gene: Muc2 (mucin 2, oligomeric mucus/gel-forming) Rattus norvegicus
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Symbol: Muc2
Name: mucin 2, oligomeric mucus/gel-forming
Description: Exhibits protein homodimerization activity; involved in several processes, including cellular response to tumor necrosis factor, response to hormone, and response to lipopolysaccharide; localizes to the cytoplasm, mucus layer, and nucleus; used to study colitis, intestinal disease, and pneumonia; biomarker of several diseases, including colitis, colon cancer, cystic fibrosis, ischemia, and liver cirrhosis; orthologous to human MUC2 (mucin 2, oligomeric mucus/gel-forming); PARTICIPATES IN Entamoebiasis pathway; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: HH-Muc; intestinal mucin-2; LOC682800; LOC682824; LOW QUALITY PROTEIN: mucin-2; MLP; MUC-2; mucin 2; mucin-2; similar to Intestinal mucin-like protein (MLP)
Orthologs:
Homo sapiens (human) : MUC2 (mucin 2, oligomeric mucus/gel-forming)  HGNC  Alliance
Mus musculus (house mouse) : Muc2 (mucin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Canis lupus familiaris (dog) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
Sus scrofa (pig) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01214,663,929 - 214,693,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01221,581,822 - 221,611,451 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1194,458,772 - 194,461,359 (+)NCBICelera
Celera1194,430,946 - 194,458,668 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Muc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3123
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.