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Gene: Myl3 (myosin light chain 3) Rattus norvegicus
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Symbol: Myl3
Name: myosin light chain 3
Description: Exhibits motor activity. Involved in cardiac muscle contraction and skeletal muscle tissue development. Localizes to the myosin complex. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy 8. Orthologous to human MYL3 (myosin light chain 3); PARTICIPATES IN prostaglandin I2 signaling pathway; dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH (RS)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93574; MLC1SB; MLClV; Mylc1v; myosin alkali light chain 1, ventricular; myosin light chain 1, slow-twitch muscle B/ventricular isoform; Myosin light chain 3 alkali cardiac ventricles; Myosin light chain 3, alkali, cardiac ventricles; myosin, light chain 3, alkali; myosin, light chain 3, alkali; ventricular, skeletal, slow; myosin, light polypeptide 3; rVMLC1; ventricular myosin light chain 1; ventricular, skeletal, slow; ventricular/slow twitch myosin alkali light chain
Orthologs:
Homo sapiens (human) : MYL3 (myosin light chain 3)  HGNC  Alliance
Mus musculus (house mouse) : Myl3 (myosin, light polypeptide 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myl3 (myosin light chain 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MYL3 (myosin light chain 3)
Canis lupus familiaris (dog) : MYL3 (myosin light chain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myl3 (myosin light chain 3)
Sus scrofa (pig) : MYL3 (myosin light chain 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08119,030,852 - 119,036,996 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08118,370,030 - 118,376,218 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,140,705 - 115,146,827 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18115,160,166 - 115,166,273 (+)NCBI
Celera8110,021,445 - 110,027,566 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Myl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3142
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.