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Gene: Nfkbia (NFKB inhibitor alpha) Rattus norvegicus
Symbol: Nfkbia
Name: NFKB inhibitor alpha
Description: Exhibits NF-kappaB binding activity and heat shock protein binding activity. Involved in several processes, including cellular response to cytokine stimulus; cytoplasmic sequestering of NF-kappaB; and liver regeneration. Localizes to cytosol; nucleus; and protein-containing complex. Used to study gastritis; pulmonary emphysema; and sciatic neuropathy. Biomarker of several diseases, including alcoholic hepatitis; artery disease (multiple); encephalitis; endometriosis; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); hypohidrotic ectodermal dysplasia; lung cancer; melanoma; and prostate cancer. Orthologous to human NFKBIA (NFKB inhibitor alpha); PARTICIPATES IN adenosine signaling pathway; ceramide signaling pathway; interleukin-23 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (+)-Tetrandrine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: I-kappa-B-alpha; ikappaBalpha; ikB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; NF-kappa-B inhibitor alpha; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; RL/IF-1
Homo sapiens (human) : NFKBIA (NFKB inhibitor alpha)  HGNC  Alliance
Mus musculus (house mouse) : Nfkbia (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfkbia (NFKB inhibitor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : NFKBIA (NFKB inhibitor alpha)
Canis lupus familiaris (dog) : NFKBIA (NFKB inhibitor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfkbia (NFKB inhibitor alpha)
Sus scrofa (pig) : NFKBIA (NFKB inhibitor alpha)
Chlorocebus sabaeus (African green monkey) : NFKBIA (NFKB inhibitor alpha)
Heterocephalus glaber (naked mole-rat) : Nfkbia (NFKB inhibitor alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0676,267,227 - 76,270,457 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,267,228 - 76,270,457 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,803,990 - 85,807,223 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,729,302 - 75,732,475 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1675,732,430 - 75,735,531 (-)NCBI
Celera671,699,196 - 71,702,411 (-)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data