Gene: Nos2 (nitric oxide synthase 2) Rattus norvegicus
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Symbol: Nos2
Name: nitric oxide synthase 2
Description: Exhibits several functions, including Hsp90 protein binding activity, actin binding activity, and enzyme binding activity; involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, cellular response to cytokine stimulus, and cellular response to lipid; localizes to several cellular components, including the cytoplasm, extracellular space, and intracellular membrane-bounded organelle; used to study several diseases, including Alzheimer's disease, asthma, diabetic angiopathy, lung disease, and pleurisy; biomarker of several diseases, including artery disease (multiple), eye disease (multiple), inflammatory bowel disease (multiple), liver disease (multiple), and lung disease (multiple); orthologous to human NOS2 (nitric oxide synthase 2); PARTICIPATES IN endothelin signaling pathway; hypoxia inducible factor pathway; interleukin-12 signaling pathway; INTERACTS WITH (+)-pilocarpine; (+)-sesamin; (+)-Tetrandrine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: inducible nitric oxide synthase; inducible NO synthase; inducible NOS; iNos; Nitric oxide synthase 2 inducible; Nitric oxide synthase 2 inducible macrophage; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase, inducible; NOS type II; Nos2a; peptidyl-cysteine S-nitrosylase NOS2
Orthologs:
Homo sapiens (human) : NOS2 (nitric oxide synthase 2)  HGNC  Alliance
Mus musculus (house mouse) : Nos2 (nitric oxide synthase 2, inducible)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nos2 (nitric oxide synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS2 (nitric oxide synthase 2)
Canis lupus familiaris (dog) : NOS2 (nitric oxide synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos2 (nitric oxide synthase 2)
Sus scrofa (pig) : NOS2 (nitric oxide synthase 2)
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Is Marker For: Strains:   SS.LEW-(Nos2-D10M11Mit119)/Ayd   SS.MNS-(D10Mco10-Aldoc)/Jr   SS.MNS-(Aldoc-D10Mco1)/Jr  
QTLs:   Bp12   Bp76   Bp133  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01066,188,290 - 66,221,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01065,423,626 - 65,456,957 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41065,036,884 - 65,072,453 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11065,050,519 - 65,086,394 (+)NCBI
Celera1062,790,940 - 62,826,625 (+)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model