Gene: Notch1 (notch receptor 1) Rattus norvegicus
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Symbol: Notch1
Name: notch receptor 1
Description: Exhibits transmembrane signaling receptor activity; involved in several processes, including animal organ development, nervous system development, and positive regulation of cell differentiation; localizes to the cytoplasm, intracellular organelle, and plasma membrane; orthologous to human NOTCH1 (notch receptor 1); PARTICIPATES IN Notch signaling pathway; Notch signaling pathway; Notch signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2-tert-butylhydroquinone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Drosophila Notch homolog 1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); neurogenic locus notch homolog protein 1; NOTCH; notch 1; Notch gene homolog 1; Notch gene homolog 1 (Drosophila); Notch homolog 1, translocation-associated; Notch homolog 1, translocation-associated (Drosophila); TAN1
Orthologs:
Homo sapiens (human) : NOTCH1 (notch receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Notch1 (notch 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Notch1 (notch receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NOTCH1 (notch receptor 1)
Canis lupus familiaris (dog) : NOTCH1 (notch receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Notch1 (notch receptor 1)
Sus scrofa (pig) : NOTCH1 (notch receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.033,905,562 - 3,951,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.039,266,663 - 9,311,575 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,631,797 - 4,677,640 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.134,632,997 - 4,677,652 (-)NCBI
Celera34,097,915 - 4,143,369 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Notch1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3187
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.