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Gene: Nr4a2 (nuclear receptor subfamily 4, group A, member 2) Rattus norvegicus
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Symbol: Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II; response to inorganic substance; and response to insecticide. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: nuclear orphan receptor HZF-3; nuclear receptor subfamily 4 group A member 2; nuclear receptor subfamily 4 group A member 2 variant NURR1a; nuclear receptor subfamily 4 group A member 2 variant NURR1b; nuclear receptor subfamily 4 group A member 2 variant NURR1c; nuclear receptor subfamily 4 group A member 2 variant NURR2c; nuclear receptor subfamily 4 group A member 2 variant TINUR; nur related protein 1; NUR-related factor 1; Nurr1; orphan nuclear receptor NURR1; orphan receptor; regenerating liver nuclear receptor 1; RNR-1; SL-322
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0343,111,258 - 43,128,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0348,183,106 - 48,192,467 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4338,866,205 - 38,871,678 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1338,763,218 - 38,769,911 (-)NCBI
Celera339,783,304 - 39,788,777 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr4a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3202
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.