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Gene: Musk (muscle associated receptor tyrosine kinase) Rattus norvegicus
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Symbol: Musk
Name: muscle associated receptor tyrosine kinase
Description: Exhibits protein kinase binding activity and protein tyrosine kinase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of synaptic transmission; and sensory organ development. Localizes to cell projection; external side of plasma membrane; and neuromuscular junction. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 9 and fetal akinesia deformation sequence syndrome 1. Orthologous to human MUSK (muscle associated receptor tyrosine kinase); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH 1-naphthyl isothiocyanate; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: muscle specific kinase (neural fold/somite kinase 1); muscle, skeletal receptor tyrosine protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific tyrosine kinase receptor MuSK; muscle-specific tyrosine protein kinase receptor; Nsk1
Orthologs:
Homo sapiens (human) : MUSK (muscle associated receptor tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Musk (muscle, skeletal, receptor tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Musk (muscle associated receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : MUSK (muscle associated receptor tyrosine kinase)
Canis lupus familiaris (dog) : MUSK (muscle associated receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Musk (muscle associated receptor tyrosine kinase)
Sus scrofa (pig) : MUSK (muscle associated receptor tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : MUSK (muscle associated receptor tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Musk (muscle associated receptor tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0575,392,790 - 75,498,694 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl575,392,790 - 75,498,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0579,542,952 - 79,649,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4576,273,430 - 76,388,614 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1576,278,542 - 76,393,727 (+)NCBI
Celera571,894,778 - 71,996,416 (+)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Musk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3211
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.