Gene: Oprm1 (opioid receptor, mu 1) Rattus norvegicus
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Symbol: Oprm1
Name: opioid receptor, mu 1
Description: Exhibits several functions, including G-protein beta-subunit binding activity, filamin binding activity, and morphine receptor activity; involved in several processes, including G protein-coupled receptor signaling pathway, regulation of signal transduction, and response to alkaloid; localizes to several cellular components, including the focal adhesion, intrinsic component of plasma membrane, and neuron projection; colocalizes with the sarcolemma; biomarker of brain ischemia and human immunodeficiency virus infectious disease; orthologous to human OPRM1 (opioid receptor mu 1); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; (3,4-dihydroxyphenyl)acetic acid; (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: M-OR-1; MOR-1; MORA; mu opioid receptor; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; mu-type opioid receptor; MUOR1; opioid receptor B; Oprm; Oprrm1
Orthologs:
Homo sapiens (human) : OPRM1 (opioid receptor mu 1)  HGNC  Alliance
Mus musculus (house mouse) : Oprm1 (opioid receptor, mu 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprm1 (opioid receptor mu 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRM1 (opioid receptor mu 1)
Canis lupus familiaris (dog) : OPRM1 (opioid receptor mu 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprm1 (opioid receptor mu 1)
Sus scrofa (pig) : OPRM1 (opioid receptor mu 1)
more info ...
Allele / Splice: Oprm1_v3   Oprm1_v1   Oprm1_v2   Oprm1_v4  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0143,454,803 - 43,704,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0144,804,181 - 45,034,145 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4137,535,416 - 37,779,392 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1137,538,384 - 37,591,800 (+)NCBI
Celera138,804,246 - 39,057,359 (+)NCBICelera
Cytogenetic Map1q11NCBI
RH 3.4 Map1468.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Oprm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3234
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.