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Gene: Otx1 (orthodenticle homeobox 1) Rattus norvegicus
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Symbol: Otx1
Name: orthodenticle homeobox 1
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including brain development; inner ear morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human OTX1 (orthodenticle homeobox 1); INTERACTS WITH bisphenol A; ethanol; paracetamol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein OTX1; homeobox protein OTX1-like; LOC100364498; Orthodenticle (Drosophila) homolog 1; orthodenticle homolog 1 (Drosophila); OTX1X
Orthologs:
Homo sapiens (human) : OTX1 (orthodenticle homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Otx1 (orthodenticle homeobox 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Otx1 (orthodenticle homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OTX1 (orthodenticle homeobox 1)
Canis lupus familiaris (dog) : OTX1 (orthodenticle homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Otx1 (orthodenticle homeobox 1)
Sus scrofa (pig) : OTX1 (orthodenticle homeobox 1)
Chlorocebus sabaeus (African green monkey) : OTX1 (orthodenticle homeobox 1)
Heterocephalus glaber (naked mole-rat) : Otx1 (orthodenticle homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.014106,861,556 - 106,864,933 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14106,861,676 - 106,864,892 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014106,926,505 - 106,929,875 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414102,721,413 - 102,724,748 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.114102,740,623 - 102,743,959 (-)NCBI
Celera1495,081,129 - 95,084,585 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Otx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3237
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.