Gene: Pcsk6 (proprotein convertase subtilisin/kexin type 6) Rattus norvegicus
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Symbol: Pcsk6
Name: proprotein convertase subtilisin/kexin type 6
Description: Predicted to have heparin binding activity, nerve growth factor binding activity, and serine-type endopeptidase activity; involved in peptide hormone processing; predicted to localize to several cellular components, including the cell surface, collagen-containing extracellular matrix, and extracellular space; orthologous to human PCSK6 (proprotein convertase subtilisin/kexin type 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: kexin-like protease PC7A; PACE4; paired basic amino acid cleaving enzyme 4; Spc4; Subtilisin - like endoprotease; subtilisin-like proprotein convertase 4; subtilisin/kexin-like protease PACE4
Orthologs:
Homo sapiens (human) : PCSK6 (proprotein convertase subtilisin/kexin type 6)  HGNC  Alliance
Mus musculus (house mouse) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Canis lupus familiaris (dog) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
Sus scrofa (pig) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01126,749,508 - 126,947,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01127,884,080 - 128,033,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41120,324,843 - 120,476,913 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11120,403,185 - 120,555,256 (+)NCBI
Celera1111,644,666 - 111,839,248 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pcsk6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3246
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.