Gene: Pak3 (p21 (RAC1) activated kinase 3) Rattus norvegicus
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Symbol: Pak3
Name: p21 (RAC1) activated kinase 3
Description: Exhibits GTPase binding activity and protein serine/threonine kinase activity; involved in several processes, including positive regulation of DNA biosynthetic process, positive regulation of dendritic spine morphogenesis, and positive regulation of fibroblast migration; localizes to the endosome; orthologous to human PAK3 (p21 (RAC1) activated kinase 3); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-PAK; p21 (CDKN1A)-activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; p21-activated kinase 3; p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p65-PAK; PAK-3; serine/threonine-protein kinase PAK 3
Orthologs:
Homo sapiens (human) : PAK3 (p21 (RAC1) activated kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Pak3 (p21 (RAC1) activated kinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak3 (p21 (RAC1) activated kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK3 (p21 (RAC1) activated kinase 3)
Canis lupus familiaris (dog) : PAK3 (p21 (RAC1) activated kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pak3 (p21 (RAC1) activated kinase 3)
Sus scrofa (pig) : PAK3 (p21 (RAC1) activated kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X114,784,452 - 115,042,683 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X113,227,320 - 113,495,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X34,734,814 - 34,842,093 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X34,788,282 - 34,895,562 (-)NCBI
CeleraX106,660,352 - 106,767,478 (+)NCBICelera
Cytogenetic MapXq33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pak3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3251
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.