Gene: Pam (peptidylglycine alpha-amidating monooxygenase) Rattus norvegicus
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Symbol: Pam
Name: peptidylglycine alpha-amidating monooxygenase
Description: Exhibits several functions, including metal ion binding activity, peptidylamidoglycolate lyase activity, and peptidylglycine monooxygenase activity; involved in several processes, including animal organ development, central nervous system development, and limb development; localizes to several cellular components, including the cell surface, cytoplasm, and extracellular space; biomarker of hypothyroidism; orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase); PARTICIPATES IN melanocortin system pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: peptidyl-glycine alpha-amidating monooxygenase; PHM
Orthologs:
Homo sapiens (human) : PAM (peptidylglycine alpha-amidating monooxygenase)  HGNC  Alliance
Mus musculus (house mouse) : Pam (peptidylglycine alpha-amidating monooxygenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pam (peptidylglycine alpha-amidating monooxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : PAM (peptidylglycine alpha-amidating monooxygenase)
Canis lupus familiaris (dog) : PAM (peptidylglycine alpha-amidating monooxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pam (peptidylglycine alpha-amidating monooxygenase)
Sus scrofa (pig) : PAM (peptidylglycine alpha-amidating monooxygenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.09111,028,543 - 111,177,588 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.09110,584,141 - 110,737,487 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4996,893,071 - 97,047,523 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1997,102,550 - 97,257,003 (+)NCBI
Celera995,564,414 - 95,713,546 (+)NCBICelera
Cytogenetic Map9q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pam
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3252
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.