Gene: Pax6 (paired box 6) Rattus norvegicus
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Symbol: Pax6
Name: paired box 6
Description: Exhibits AT DNA binding activity; involved in several processes, including animal organ development, cellular response to hormone stimulus, and nervous system development; localizes to the nuclear chromatin; used to study autistic disorder; biomarker of Smith-Lemli-Opitz syndrome and transient cerebral ischemia; orthologous to human PAX6 (paired box 6); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: oculorhombin; paired box gene 6; Paired box homeotic gene 6; paired box protein Pax-6
Orthologs:
Homo sapiens (human) : PAX6 (paired box 6)  HGNC  Alliance
Mus musculus (house mouse) : Pax6 (paired box 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pax6 (paired box 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAX6 (paired box 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pax6 (paired box 6)
Sus scrofa (pig) : PAX6 (paired box 6)
more info ...
Allele / Splice: Pax6Sey   Pax6Sey2  
Genetic Models: SD-Pax6Sey2/Mce SD-Pax6Sey/Mce
Is Marker For: Strains:   SD-Pax6Sey/Mce  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0395,700,241 - 95,728,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03102,320,059 - 102,348,223 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4391,127,605 - 91,149,178 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1391,023,827 - 91,045,776 (+)NCBI
Celera391,190,477 - 91,211,449 (+)NCBICelera
Cytogenetic Map3q33NCBI
RH 3.4 Map3722.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pax6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3258
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.