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Gene: Pfkl (phosphofructokinase, liver type) Rattus norvegicus
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Symbol: Pfkl
Name: phosphofructokinase, liver type
Description: Exhibits 6-phosphofructokinase activity; anion binding activity; and monosaccharide binding activity. Involved in several processes, including fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; and protein homotetramerization. Localizes to the cytosol. Orthologous to human PFKL (phosphofructokinase, liver type); PARTICIPATES IN glycolysis pathway; glycolysis/gluconeogenesis pathway; fructose and mannose metabolic pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 6-phosphofructokinase type B; 6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type; ATP-PFK; PFK-B; PFK-L; phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphofructokinase, liver; phosphofructokinase, liver, B-type; phosphohexokinase
Orthologs:
Homo sapiens (human) : PFKL (phosphofructokinase, liver type)  HGNC  Alliance
Mus musculus (house mouse) : Pfkl (phosphofructokinase, liver, B-type)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pfkl (phosphofructokinase, liver type)
Pan paniscus (bonobo/pygmy chimpanzee) : PFKL (phosphofructokinase, liver type)
Canis lupus familiaris (dog) : PFKL (phosphofructokinase, liver type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pfkl (phosphofructokinase, liver type)
Sus scrofa (pig) : PFKL (phosphofructokinase, liver type)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02011,393,860 - 11,415,889 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02013,563,748 - 13,585,941 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42011,009,359 - 11,032,511 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12011,009,585 - 11,032,737 (+)NCBI
Celera2012,170,125 - 12,192,155 (+)NCBICelera
Cytogenetic Map20p12NCBI
RH 3.4 Map20140.5RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pfkl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3311
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.