Gene: Abcb1b (ATP-binding cassette, subfamily B (MDR/TAP), member 1B) Rattus norvegicus
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Symbol: Abcb1b
Name: ATP-binding cassette, subfamily B (MDR/TAP), member 1B
Description: Exhibits transporter activity; involved in several processes, including Sertoli cell barrier remodeling, animal organ development, and cellular response to external biotic stimulus; localizes to the Golgi membrane and apical plasma membrane; used to study brain disease (multiple), colorectal adenocarcinoma, end stage renal failure, human immunodeficiency virus infectious disease, and malignant glioma; biomarker of several diseases, including brain disease (multiple), brain ischemia, cholestasis, human immunodeficiency virus infectious disease, and nonalcoholic fatty liver disease; orthologous to human ABCB1 (ATP binding cassette subfamily B member 1); PARTICIPATES IN bile acid transport pathway; INTERACTS WITH (+)-pilocarpine; 1,2-dimethylhydrazine; 1,9-dideoxyforskolin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Abcb1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, subfamily B, member 1B; Mdr1; mdr1b; multidrug resistance protein 1; P-glycoprotein 1; P-glycoprotein/multidrug resistance 1; Pgy1
Orthologs:
Allele / Splice: Abcb1bem2Mcwi  
Genetic Models: SS-Abcb1bem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0422,225,123 - 22,307,577 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0422,161,597 - 22,244,735 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4421,829,489 - 21,912,239 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1421,829,488 - 21,912,239 (+)NCBI
Celera420,736,092 - 20,817,649 (-)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcb1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3318
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.