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Gene: Pitx3 (paired-like homeodomain 3) Rattus norvegicus
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Symbol: Pitx3
Name: paired-like homeodomain 3
Description: Exhibits DNA-binding transcription factor activity. Involved in several processes, including aging; regulation of nervous system development; and response to alkaloid. Localizes to the neuronal cell body and nucleus. Human ortholog(s) of this gene implicated in anterior segment mesenchymal dysgenesis; cataract; cataract 11 multiple types; and cataract 9 multiple types. Orthologous to human PITX3 (paired like homeodomain 3); INTERACTS WITH 17beta-estradiol 3-benzoate; 5-azacytidine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein PITX3; homeobox protein PTX3; paired-like homeodomain transcription factor 3; pituitary homeobox 3
Orthologs:
Homo sapiens (human) : PITX3 (paired like homeodomain 3)  HGNC  Alliance
Mus musculus (house mouse) : Pitx3 (paired-like homeodomain transcription factor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pitx3 (paired like homeodomain 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PITX3 (paired like homeodomain 3)
Canis lupus familiaris (dog) : PITX3 (paired like homeodomain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pitx3 (paired like homeodomain 3)
Sus scrofa (pig) : PITX3 (paired like homeodomain 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01265,886,766 - 265,899,947 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01273,317,125 - 273,330,306 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,355,785 - 251,368,502 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,616,353 - 251,629,068 (-)NCBI
Celera1240,784,495 - 240,797,213 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pitx3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3332
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.