Gene: Plcb4 (phospholipase C, beta 4) Rattus norvegicus
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Symbol: Plcb4
Name: phospholipase C, beta 4
Description: Exhibits mitogen-activated protein kinase binding activity; involved in negative regulation of potassium ion transport; localizes to the cytoplasm; orthologous to human PLCB4 (phospholipase C beta 4); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; Alzheimer's disease pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; Beta4aa; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-4; Phospholipase C (BETA4); Phospholipase C beta4; phospholipase C-beta-4; PLC-beta-4; RATBETA4AA
Orthologs:
Homo sapiens (human) : PLCB4 (phospholipase C beta 4)  HGNC  Alliance
Mus musculus (house mouse) : Plcb4 (phospholipase C, beta 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb4 (phospholipase C beta 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB4 (phospholipase C beta 4)
Canis lupus familiaris (dog) : PLCB4 (phospholipase C beta 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb4 (phospholipase C beta 4)
Sus scrofa (pig) : PLCB4 (phospholipase C beta 4)
more info ...
Allele / Splice: Plcb4_v1   Plcb4_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03128,601,163 - 128,971,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03135,089,551 - 135,459,248 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43123,706,313 - 124,077,381 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13123,611,885 - 123,982,941 (+)NCBI
Celera3121,694,557 - 122,062,160 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plcb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3345
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.