Gene: Plcg1 (phospholipase C, gamma 1) Rattus norvegicus
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Symbol: Plcg1
Name: phospholipase C, gamma 1
Description: Exhibits insulin receptor binding activity and phosphoprotein binding activity. Involved in several processes, including inositol trisphosphate biosynthetic process; regulation of store-operated calcium channel activity; and response to morphine. Localizes to the clathrin-coated vesicle. Colocalizes with the neuron projection. Orthologous to human PLCG1 (phospholipase C gamma 1); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH (+)-dihydromyricetin; (R)-noradrenaline; (RS)-amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C-gamma-1; PLC-148; PLC-gamma-1; PLC-II; PPLCA
Orthologs:
Homo sapiens (human) : PLCG1 (phospholipase C gamma 1)  HGNC  Alliance
Mus musculus (house mouse) : Plcg1 (phospholipase C, gamma 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcg1 (phospholipase C gamma 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCG1 (phospholipase C gamma 1)
Canis lupus familiaris (dog) : PLCG1 (phospholipase C gamma 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcg1 (phospholipase C gamma 1)
Sus scrofa (pig) : PLCG1 (phospholipase C gamma 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03156,727,642 - 156,758,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03162,957,126 - 162,987,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,522,949 - 151,553,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13151,428,984 - 151,460,034 (+)NCBI
Celera3148,059,477 - 148,090,220 (+)NCBICelera
Cytogenetic Map3q42NCBI
RH 3.4 Map31368.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plcg1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3347
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.