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Gene: Pld2 (phospholipase D2) Rattus norvegicus
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Symbol: Pld2
Name: phospholipase D2
Description: Exhibits phospholipase D activity and protein kinase C binding activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of vesicle-mediated transport; and response to hydrogen peroxide. Localizes to several cellular components, including the Golgi apparatus; caveola; and sarcolemma. Biomarker of congestive heart failure and visual epilepsy. Orthologous to human PLD2 (phospholipase D2); PARTICIPATES IN Arf family mediated signaling pathway; glycerophospholipid metabolic pathway; mTOR signaling pathway; INTERACTS WITH (RS)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: choline phosphatase 2; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D gene 2; PLD 2; PLD1C; Pldc; rPLD2
Orthologs:
Homo sapiens (human) : PLD2 (phospholipase D2)  HGNC  Alliance
Mus musculus (house mouse) : Pld2 (phospholipase D2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld2 (phospholipase D2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD2 (phospholipase D2)
Canis lupus familiaris (dog) : PLD2 (phospholipase D2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld2 (phospholipase D2)
Sus scrofa (pig) : PLD2 (phospholipase D2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01057,161,921 - 57,181,148 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,908,891 - 56,926,691 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,388,474 - 57,439,063 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11057,402,096 - 57,452,684 (+)NCBI
Celera1054,402,188 - 54,419,867 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pld2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3350
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.