Gene: Plk1 (polo-like kinase 1) Rattus norvegicus
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Symbol: Plk1
Name: polo-like kinase 1
Description: Predicted to have several functions, including ATP binding activity, anaphase-promoting complex binding activity, and identical protein binding activity; involved in polar body extrusion after meiotic divisions, protein phosphorylation, and response to antibiotic; localizes to the cytoplasm and intracellular organelle; predicted to colocalize with the spindle microtubule; orthologous to human PLK1 (polo like kinase 1); PARTICIPATES IN cell cycle pathway, mitotic; M phase pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Plk; PLK-1; polo-like kinase 1 (Drosophila); polo-like kinase homolog; polo-like kinase homolog (Drosophila); serine/threonine-protein kinase PLK1
Orthologs:
Homo sapiens (human) : PLK1 (polo like kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Plk1 (polo like kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plk1 (polo like kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLK1 (polo like kinase 1)
Canis lupus familiaris (dog) : PLK1 (polo like kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk1 (polo like kinase 1)
Sus scrofa (pig) : PLK1 (polo like kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01192,115,990 - 192,125,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01199,178,259 - 199,188,238 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,002,811 - 181,012,741 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11181,142,728 - 181,152,656 (+)NCBI
Celera1174,424,809 - 174,434,922 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3352
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.