Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Plk1 (polo-like kinase 1) Rattus norvegicus
Analyze
Symbol: Plk1
Name: polo-like kinase 1
Description: Predicted to have several functions, including ATP binding activity; anaphase-promoting complex binding activity; and magnesium ion binding activity. Involved in polar body extrusion after meiotic divisions; protein phosphorylation; and response to antibiotic. Localizes to cytoplasm; nucleus; and spindle. Predicted to colocalize with spindle microtubule. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human PLK1 (polo like kinase 1); PARTICIPATES IN cell cycle pathway, mitotic; M phase pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Plk; PLK-1; polo-like kinase 1 (Drosophila); polo-like kinase homolog; polo-like kinase homolog (Drosophila); serine/threonine-protein kinase PLK1
Orthologs:
Homo sapiens (human) : PLK1 (polo like kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Plk1 (polo like kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plk1 (polo like kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLK1 (polo like kinase 1)
Canis lupus familiaris (dog) : PLK1 (polo like kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk1 (polo like kinase 1)
Sus scrofa (pig) : PLK1 (polo like kinase 1)
Chlorocebus sabaeus (African green monkey) : PLK1 (polo like kinase 1)
Heterocephalus glaber (naked mole-rat) : Plk1 (polo like kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01192,115,990 - 192,125,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1192,115,966 - 192,125,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01199,178,259 - 199,188,238 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,002,811 - 181,012,741 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11181,142,728 - 181,152,656 (+)NCBI
Celera1174,424,809 - 174,434,922 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3352
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.