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Gene: Polb (DNA polymerase beta) Rattus norvegicus
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Symbol: Polb
Name: DNA polymerase beta
Description: Exhibits DNA-directed DNA polymerase activity; damaged DNA binding activity; and metal ion binding activity. Involved in several processes, including DNA repair; response to gamma radiation; and response to hyperoxia. Localizes to the nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human POLB (DNA polymerase beta); PARTICIPATES IN base excision repair pathway; INTERACTS WITH (15Z)-tetracosenoic acid; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA pol beta; DNA-directed DNA polymerase beta; polymerase (DNA directed), beta; polymerase (DNA) beta; polymerase-beta
Orthologs:
Homo sapiens (human) : POLB (DNA polymerase beta)  HGNC  Alliance
Mus musculus (house mouse) : Polb (polymerase (DNA directed), beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polb (DNA polymerase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : POLB (DNA polymerase beta)
Canis lupus familiaris (dog) : POLB (DNA polymerase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polb (DNA polymerase beta)
Sus scrofa (pig) : POLB (DNA polymerase beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01674,237,001 - 74,260,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1674,237,001 - 74,260,271 (+)Ensembl
Rnor_5.01673,869,828 - 73,893,106 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,864,702 - 73,888,011 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,864,971 - 73,890,378 (+)NCBI
Celera1667,272,411 - 67,295,648 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Polb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3363
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.