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Gene: Pomc (proopiomelanocortin) Rattus norvegicus
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Symbol: Pomc
Name: proopiomelanocortin
Description: Predicted to have hormone activity and melanocortin receptor binding activity. Predicted to be involved in several processes, including cortisol secretion; positive regulation of neutrophil mediated killing of fungus; and regulation of corticosterone secretion. Localizes to extracellular region. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Orthologous to human POMC (proopiomelanocortin); PARTICIPATES IN alfentanil pharmacodynamics pathway; altered energy homeostasis pathway; altered melanocortin system pathway; INTERACTS WITH (S)-colchicine; (S)-nicotine; (Z)-hex-3-en-1-ol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-melanocyte-stimulating hormone; alphaMSH; corticotropin-lipotropin; Pomc1; Pomc2; pro-opiomelanocortin; pro-opiomelanocortin-alpha; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin, beta (endorphin, beta); proopoimelanocortin, beta (endorphin, beta)
Orthologs:
Homo sapiens (human) : POMC (proopiomelanocortin)  HGNC  Alliance
Mus musculus (house mouse) : Pomc (pro-opiomelanocortin-alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pomc (proopiomelanocortin)
Pan paniscus (bonobo/pygmy chimpanzee) : POMC (proopiomelanocortin)
Canis lupus familiaris (dog) : POMC (proopiomelanocortin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pomc (proopiomelanocortin)
Sus scrofa (pig) : POMC (proopiomelanocortin)
Chlorocebus sabaeus (African green monkey) : POMC (proopiomelanocortin)
Heterocephalus glaber (naked mole-rat) : Pomc (proopiomelanocortin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0628,382,937 - 28,388,771 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl628,382,962 - 28,388,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0638,191,989 - 38,197,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,931,969 - 26,937,789 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1626,934,921 - 26,940,742 (+)NCBI
Celera626,415,706 - 26,421,526 (+)NCBICelera
Cytogenetic Map6q14NCBI
RH 3.4 Map6117.99RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pomc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3366
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.