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Gene: Pou1f1 (POU class 1 homeobox 1) Rattus norvegicus
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Symbol: Pou1f1
Name: POU class 1 homeobox 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in adenohypophysis development; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Localizes to the nucleus. Colocalizes with the chromatin. Human ortholog(s) of this gene implicated in panhypopituitarism and pituitary gland disease. Orthologous to human POU1F1 (POU class 1 homeobox 1); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GHF-1; GHF1; GHF1A; growth hormone factor 1; homeodomain protein for Growth Hormone (GH); pit-1; Pit1; PIT1Z; Pituary specific transcription factor 1 (growth hormone factor 1); pituitary-specific positive transcription factor 1; pituitary-specific positive transcription factor 1 variant w; POU domain, class 1, transcription factor 1
Orthologs:
Homo sapiens (human) : POU1F1 (POU class 1 homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Pou1f1 (POU domain, class 1, transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou1f1 (POU class 1 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU1F1 (POU class 1 homeobox 1)
Canis lupus familiaris (dog) : POU1F1 (POU class 1 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou1f1 (POU class 1 homeobox 1)
Sus scrofa (pig) : POU1F1 (POU class 1 homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0112,645,659 - 2,662,581 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl112,645,865 - 2,662,579 (+)Ensembl
Rnor_5.0112,630,048 - 2,647,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4112,959,383 - 2,980,545 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1112,959,382 - 2,980,543 (+)NCBI
Celera113,294,195 - 3,311,824 (+)NCBICelera
Cytogenetic Map11p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pou1f1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3367
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.