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Gene: Ppara (peroxisome proliferator activated receptor alpha) Rattus norvegicus
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Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Description: Exhibits several functions, including MDM2/MDM4 family protein binding activity; nuclear receptor activity; and transcription factor binding activity. Involved in several processes, including behavioral response to nicotine; negative regulation of cell growth involved in cardiac muscle cell development; and response to insulin. Localizes to nucleus. Used to study hepatocellular carcinoma; hypertension; hypertensive encephalopathy; and periodontitis. Biomarker of alcoholic hepatitis; fatty liver disease; hydrocephalus; and hypertension. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha); PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; hepatitis C pathway; INTERACTS WITH (+)-catechin; (+)-schisandrin B; (R)-carnitine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: nuclear receptor subfamily 1 group C member 1; peroxisome proliferator-activated receptor alpha; PPAR; PPAR-alpha
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07126,618,872 - 126,687,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,619,196 - 126,681,752 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07126,330,559 - 126,397,441 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47123,729,774 - 123,807,090 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17123,764,003 - 123,841,320 (+)NCBI
Celera7113,125,201 - 113,187,404 (+)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7922.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences