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Gene: Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent, 1B) Rattus norvegicus
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Symbol: Ppm1b
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1B
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in several processes, including cellular protein modification process; negative regulation of defense response to virus; and regulation of signal transduction. Predicted to localize to the cytosol; membrane; and nucleolus. Orthologous to human PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: PP2C-beta; Pp2c2; protein phosphatase 1B; protein phosphatase 1B, magnesium dependent, beta isoform; protein phosphatase 2C isoform beta; Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform; Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform
Orthologs:
Homo sapiens (human) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)  HGNC  Alliance
Mus musculus (house mouse) : Ppm1b (protein phosphatase 1B, magnesium dependent, beta isoform)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Canis lupus familiaris (dog) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Sus scrofa (pig) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.068,219,385 - 8,280,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl68,218,696 - 8,280,124 (+)Ensembl
Rnor_5.068,151,741 - 8,212,739 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,319,544 - 8,373,795 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.168,319,543 - 8,373,795 (+)NCBI
Celera69,370,886 - 9,431,637 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ppm1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3374
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.