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Gene: Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent, 1B) Rattus norvegicus
Symbol: Ppm1b
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1B
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in several processes, including cellular protein modification process; negative regulation of defense response to virus; and regulation of signal transduction. Predicted to localize to the cytosol; membrane; and nucleolus. Orthologous to human PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: PP2C-beta; Pp2c2; protein phosphatase 1B; protein phosphatase 1B, magnesium dependent, beta isoform; protein phosphatase 2C isoform beta; Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform; Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform
Homo sapiens (human) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)  HGNC  Alliance
Mus musculus (house mouse) : Ppm1b (protein phosphatase 1B, magnesium dependent, beta isoform)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Canis lupus familiaris (dog) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Sus scrofa (pig) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.068,219,385 - 8,280,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl68,218,696 - 8,280,124 (+)Ensembl
Rnor_5.068,151,741 - 8,212,739 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,319,544 - 8,373,795 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.168,319,543 - 8,373,795 (+)NCBI
Celera69,370,886 - 9,431,637 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ppm1b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3374
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.