Gene: Ppp3cb (protein phosphatase 3 catalytic subunit beta) Rattus norvegicus
Analyze
Symbol: Ppp3cb
Name: protein phosphatase 3 catalytic subunit beta
Description: Exhibits calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding activity, and protein heterodimerization activity; involved in several processes, including brain development, muscle cell cellular homeostasis, and positive regulation of insulin secretion involved in cellular response to glucose stimulus; localizes to the plasma membrane, protein-containing complex, and synapse; biomarker of schizophrenia; orthologous to human PPP3CB (protein phosphatase 3 catalytic subunit beta); PARTICIPATES IN calcineurin signaling pathway; dopamine signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calcineurin subunit A beta; calmodulin-dependent calcineurin A subunit beta isoform; Calna2; CAM-PRP catalytic subunit; CaN Abeta; CNA beta; protein phosphatase 3, catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase-2Bb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0154,209,702 - 4,236,895 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0158,310,717 - 8,338,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,986,290 - 4,030,352 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X153,471,064 - 153,474,197 (+)NCBI
Celera15790,760 - 817,953 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ppp3cb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3383
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.