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Gene: Prkar2a (protein kinase cAMP-dependent type II regulatory subunit alpha) Rattus norvegicus
Symbol: Prkar2a
Name: protein kinase cAMP-dependent type II regulatory subunit alpha
CRRD ID: 3393
Description: Exhibits several functions, including beta-2 adrenergic receptor binding activity; cAMP binding activity; and cAMP-dependent protein kinase regulator activity. Involved in regulation of protein kinase activity and response to clozapine. Localizes to T-tubule; cAMP-dependent protein kinase complex; and perinuclear region of cytoplasm. Predicted to colocalize with axoneme. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha); PARTICIPATES IN protein kinase A (PKA) signaling pathway; apoptotic cell death pathway; insulin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
Also known as: cAMP-dependent protein kinase type II-alpha regulatory subunit; protein kinase cAMP-dependent regulatory type II alpha; protein kinase cAMP-dependent type 2 regulatory subunit alpha; protein kinase, cAMP dependent regulatory, type II alpha; protein kinase, cAMP-dependent, regulatory subunit type II alpha; protein kinase, cAMP-dependent, regulatory, type 2, alpha; protein kinase, cAMP-dependent, regulatory, type II, alpha
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08117,486,085 - 117,548,768 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,486,083 - 117,546,370 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,830,841 - 116,893,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,746,384 - 113,805,476 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18113,765,838 - 113,824,931 (+)NCBI
Celera8108,691,132 - 108,750,351 (+)NCBICelera
Cytogenetic Map8q32NCBI
RH 3.4 Map81114.1RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Prkar2a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3393
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.