Gene: Prkca (protein kinase C, alpha) Rattus norvegicus
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Symbol: Prkca
Name: protein kinase C, alpha
Description: Exhibits calcium-dependent protein kinase C activity; involved in several processes, including cellular protein modification process, regulation of protein metabolic process, and regulation of vesicle-mediated transport; localizes to several cellular components, including the cytoplasm, membrane raft, and neuron projection; used to study hypertension; biomarker of brain ischemia, congestive heart failure, and ischemia; orthologous to human PRKCA (protein kinase C alpha); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; Fc epsilon receptor mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-nicotine; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PKC-A; PKC-alpha; Pkca; protein kinase C alpha type
Orthologs:
Homo sapiens (human) : PRKCA (protein kinase C alpha)  HGNC  Alliance
Mus musculus (house mouse) : Prkca (protein kinase C, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkca (protein kinase C alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCA (protein kinase C alpha)
Canis lupus familiaris (dog) : PRKCA (protein kinase C alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkca (protein kinase C alpha)
Sus scrofa (pig) : PRKCA (protein kinase C alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01096,186,509 - 96,585,168 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01095,919,013 - 96,311,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41097,367,196 - 97,638,910 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11097,382,023 - 97,632,491 (-)NCBI
Celera1091,557,626 - 91,951,823 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
RH 3.4 Map101035.79RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkca
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3395
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.