Gene: Prkcz (protein kinase C, zeta) Rattus norvegicus
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Symbol: Prkcz
Name: protein kinase C, zeta
Description: Exhibits several functions, including 14-3-3 protein binding activity, enzyme binding activity, and potassium channel regulator activity; involved in several processes, including activation of phospholipase D activity, activation of protein kinase B activity, and positive regulation of cell communication; localizes to several cellular components, including the Schaffer collateral - CA1 synapse, cytoplasm, and intracellular organelle; used to study hyperglycemia; biomarker of type 2 diabetes mellitus; orthologous to human PRKCZ (protein kinase C zeta); PARTICIPATES IN angiotensin II signaling pathway; epidermal growth factor/neuregulin signaling pathway; protein kinase C (PKC) signaling pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; nPKC-zeta; Pkcz; protein kinase C zeta type; r14-3-3
Orthologs:
Homo sapiens (human) : PRKCZ (protein kinase C zeta)  HGNC  Alliance
Mus musculus (house mouse) : Prkcz (protein kinase C, zeta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcz (protein kinase C zeta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCZ (protein kinase C zeta)
Canis lupus familiaris (dog) : PRKCZ (protein kinase C zeta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcz (protein kinase C zeta)
Sus scrofa (pig) : PRKCZ (protein kinase C zeta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05172,658,071 - 172,769,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05176,116,787 - 176,228,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,061,825 - 172,172,793 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15172,072,319 - 172,179,534 (-)NCBI
Celera5164,023,257 - 164,132,959 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkcz
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3399
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.