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Gene: Prkg2 (protein kinase cGMP-dependent 2) Rattus norvegicus
Symbol: Prkg2
Name: protein kinase cGMP-dependent 2
CRRD ID: 3401
Description: Exhibits cGMP-dependent protein kinase activity and identical protein binding activity. Involved in negative regulation of chloride transport; peptidyl-serine autophosphorylation; and protein localization to plasma membrane. Localizes to nuclear membrane. Orthologous to human PRKG2 (protein kinase cGMP-dependent 2); PARTICIPATES IN long term depression; INTERACTS WITH 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
Also known as: CGK 2; cGK2; cGKII; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; GDPKII; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; protein kinase, cGMP-dependent, type II; type II cGMP-dependent protein kinase
Homo sapiens (human) : PRKG2 (protein kinase cGMP-dependent 2)  HGNC  Alliance
Mus musculus (house mouse) : Prkg2 (protein kinase, cGMP-dependent, type II)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkg2 (protein kinase cGMP-dependent 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKG2 (protein kinase cGMP-dependent 2)
Canis lupus familiaris (dog) : PRKG2 (protein kinase cGMP-dependent 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkg2 (protein kinase cGMP-dependent 2)
Sus scrofa (pig) : PRKG2 (protein kinase cGMP-dependent 2)
Chlorocebus sabaeus (African green monkey) : PRKG2 (protein kinase cGMP-dependent 2)
Heterocephalus glaber (naked mole-rat) : Prkg2 (protein kinase cGMP-dependent 2)
more info ...
Is Marker For: Strains:   KMI/Tky  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01412,217,121 - 12,313,616 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1412,218,553 - 12,315,229 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01412,159,378 - 12,255,994 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41411,888,101 - 12,005,547 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11411,888,100 - 12,005,547 (+)NCBI
Celera1410,666,687 - 10,755,836 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkg2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3401
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.