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Gene: Prps2 (phosphoribosyl pyrophosphate synthetase 2) Rattus norvegicus
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Symbol: Prps2
Name: phosphoribosyl pyrophosphate synthetase 2
Description: Exhibits several functions, including magnesium ion binding activity; purine ribonucleotide binding activity; and ribose phosphate diphosphokinase activity. Involved in 5-phosphoribose 1-diphosphate biosynthetic process; AMP biosynthetic process; and animal organ regeneration. Localizes to the ribose phosphate diphosphokinase complex. Orthologous to human PRPS2 (phosphoribosyl pyrophosphate synthetase 2); PARTICIPATES IN de novo purine biosynthetic pathway; pentose phosphate pathway; purine metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Phophoribosylpyrophosphate synthetase subunit II; Phophoribosylpyrophosphate synthetase, subunit II; phosphoribosyl pyrophosphate synthase II; phosphoribosyl pyrophosphate synthetase II; PRS-II; ribose-phosphate pyrophosphokinase 2
Orthologs:
Homo sapiens (human) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)  HGNC  Alliance
Mus musculus (house mouse) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Canis lupus familiaris (dog) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Sus scrofa (pig) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
more info ...
Is Marker For: QTLs:   Iddm5  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X28,435,275 - 28,472,882 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,435,507 - 28,472,880 (+)Ensembl
Rnor_5.0X28,831,387 - 28,868,992 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,274,362 - 47,315,274 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X47,327,830 - 47,368,743 (+)NCBI
CeleraX27,388,118 - 27,424,061 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prps2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3415
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.