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Gene: Klk6 (kallikrein related-peptidase 6) Rattus norvegicus
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Symbol: Klk6
Name: kallikrein related-peptidase 6
Description: Exhibits peptidase activity. Involved in regulation of neuron projection development. Predicted to localize to the extracellular region and secretory granule. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; demyelinating disease; and multiple system atrophy. Orthologous to human KLK6 (kallikrein related peptidase 6); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: kallikrein 6; kallikrein 6 (neurosin zyme); kallikrein 6 (neurosin); kallikrein 6 (neurosin, zyme); kallikrein i; kallikrein-6; Klni; protease serine 9; protease serine 9 (neurosin); protease, serine, 9; Prss9
Orthologs:
Homo sapiens (human) : KLK6 (kallikrein related peptidase 6)  HGNC  Alliance
Mus musculus (house mouse) : Klk6 (kallikrein related-peptidase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klk6 (kallikrein related peptidase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : KLK6 (kallikrein related peptidase 6)
Canis lupus familiaris (dog) : KLK6 (kallikrein related peptidase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klk6 (kallikrein related peptidase 6)
Sus scrofa (pig) : KLK6 (kallikrein related peptidase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0199,762,195 - 99,769,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01100,830,974 - 100,838,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,254,350 - 94,261,500 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1194,332,460 - 94,339,610 (+)NCBI
Celera188,546,437 - 88,553,549 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Klk6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3419
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.