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Gene: Pth1r (parathyroid hormone 1 receptor) Rattus norvegicus
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Symbol: Pth1r
Name: parathyroid hormone 1 receptor
Description: Exhibits parathyroid hormone receptor activity and peptide hormone binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; aging; and positive regulation of inositol phosphate biosynthetic process. Localizes to several cellular components, including the apical plasma membrane; basolateral plasma membrane; and brush border membrane. Used to study hypercalcemia. Human ortholog(s) of this gene implicated in Jansen's metaphyseal chondrodysplasia; chondrodysplasia Blomstrand type; and osteochondrodysplasia. Orthologous to human PTH1R (parathyroid hormone 1 receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; parathyroid hormone signaling pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: parathyroid hormone receptor; parathyroid hormone receptor 1; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; Pthr; Pthr1; PTHrel
Orthologs:
Homo sapiens (human) : PTH1R (parathyroid hormone 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Pth1r (parathyroid hormone 1 receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pth1r (parathyroid hormone 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : PTH1R (parathyroid hormone 1 receptor)
Canis lupus familiaris (dog) : PTH1R (parathyroid hormone 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pth1r (parathyroid hormone 1 receptor)
Sus scrofa (pig) : PTH1R (parathyroid hormone 1 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08118,984,531 - 119,012,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08118,325,190 - 118,353,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,099,763 - 115,119,362 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18115,119,118 - 115,139,954 (-)NCBI
Celera8109,981,641 - 110,001,215 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pth1r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3442
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.