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Gene: Ptprj (protein tyrosine phosphatase, receptor type, J) Rattus norvegicus
Symbol: Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Description: Predicted to have several functions, including beta-catenin binding activity; delta-catenin binding activity; and gamma-catenin binding activity. Predicted to be involved in several processes, including regulation of cell migration; regulation of protein phosphorylation; and regulation of signal transduction. Predicted to localize to several cellular components, including cell surface; immunological synapse; and ruffle membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J); PARTICIPATES IN somatostatin signaling pathway; epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: density enhanced phosphatase-1; DEP-1; protein tyrosine phosphatase receptor type J; receptor-type tyrosine-protein phosphatase eta
Homo sapiens (human) : PTPRJ (protein tyrosine phosphatase receptor type J)  HGNC  Alliance
Mus musculus (house mouse) : Ptprj (protein tyrosine phosphatase, receptor type, J)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprj (protein tyrosine phosphatase receptor type J)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRJ (protein tyrosine phosphatase receptor type J)
Canis lupus familiaris (dog) : PTPRJ (protein tyrosine phosphatase receptor type J)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprj (protein tyrosine phosphatase receptor type J)
Sus scrofa (pig) : PTPRJ (protein tyrosine phosphatase receptor type J)
Chlorocebus sabaeus (African green monkey) : PTPRJ (protein tyrosine phosphatase receptor type J)
Heterocephalus glaber (naked mole-rat) : Ptprj (protein tyrosine phosphatase receptor type J)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0379,233,519 - 79,390,956 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,233,525 - 79,390,956 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0385,947,682 - 86,099,287 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4374,796,764 - 74,935,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1374,693,135 - 74,831,912 (-)NCBI
Celera375,621,921 - 75,777,388 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ptprj
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3454
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.