Gene: RT1-Bb (RT1 class II, locus Bb) Rattus norvegicus
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Symbol: RT1-Bb
Name: RT1 class II, locus Bb
Description: Exhibits protein heterodimerization activity; involved in cellular response to organic cyclic compound, negative regulation of T cell proliferation, and response to parasitic fungus; localizes to the cell surface; used to study uveitis; biomarker of pneumocystosis; orthologous to several human genes including HLA-DQB1 (major histocompatibility complex, class II, DQ beta 1); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bb; MGC94124; MHC class II antigen B beta chain; rano class II histocompatibility antigen, B-1 beta chain; RT1 class II histocompatibility antigen, B-1 beta chain; RT1-B beta; RT1.B; RT1.B-beta(1); RT1.B-BETA1; RT1.Bbeta; RT1.Bbeta 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,043,726 - 4,049,367 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,123,272 - 6,128,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,730,559 - 4,736,201 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,730,786 - 4,736,413 (-)NCBI
Celera206,197,565 - 6,203,195 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on RT1-Bb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3469
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.