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Gene: RT1-DOa (RT1 class II, locus DOa) Rattus norvegicus
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Symbol: RT1-DOa
Name: RT1 class II, locus DOa
Description: Predicted to have MHC class II protein complex binding activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of antigen processing and presentation of peptide antigen via MHC class II; and regulation of T cell differentiation. Predicted to localize to the MHC class II protein complex. Orthologous to human HLA-DOA (major histocompatibility complex, class II, DO alpha); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: H2-Oa; histocompatibility 2, O region alpha locus
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,889,106 - 3,892,360 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0205,968,563 - 5,971,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,890,410 - 4,894,048 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,890,638 - 4,894,271 (-)NCBI
Celera206,354,703 - 6,357,121 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on RT1-DOa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3477
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.