Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rasa1 (RAS p21 protein activator 1) Rattus norvegicus
Symbol: Rasa1
Name: RAS p21 protein activator 1
Description: Exhibits several functions, including GTPase activator activity; ion channel binding activity; and protein kinase binding activity. Involved in several processes, including activation of GTPase activity; cellular response to growth factor stimulus; and positive regulation of glucose import. Localizes to cytosol; nuclear membrane; and plasma membrane. Human ortholog(s) of this gene implicated in arteriovenous malformation and basal cell carcinoma. Orthologous to human RASA1 (RAS p21 protein activator 1); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
Also known as: GAP; GAPX; GTPase-activating protein; p120GAP; ras GTPase-activating protein 1; RAS p21 protein activator; RAS p21 protein activator (GTPase activating protein) 1; Rasa; rasGAP
Homo sapiens (human) : RASA1 (RAS p21 protein activator 1)  HGNC  Alliance
Mus musculus (house mouse) : Rasa1 (RAS p21 protein activator 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasa1 (RAS p21 protein activator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RASA1 (RAS p21 protein activator 1)
Canis lupus familiaris (dog) : RASA1 (RAS p21 protein activator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasa1 (RAS p21 protein activator 1)
Sus scrofa (pig) : RASA1 (RAS p21 protein activator 1)
Chlorocebus sabaeus (African green monkey) : RASA1 (RAS p21 protein activator 1)
Heterocephalus glaber (naked mole-rat) : Rasa1 (RAS p21 protein activator 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0213,617,021 - 13,696,531 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl213,616,822 - 13,696,426 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0213,470,580 - 13,551,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4214,203,815 - 14,287,824 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1214,124,183 - 14,208,193 (-)NCBI
Celera212,124,725 - 12,204,755 (-)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rasa1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3537
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.