Gene: Rgn (regucalcin) Rattus norvegicus
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Symbol: Rgn
Name: regucalcin
Description: Exhibits calcium ion binding activity and gluconolactonase activity; involved in several processes, including negative regulation of cellular metabolic process, negative regulation of hydrolase activity, and positive regulation of cellular metabolic process; localizes to the cytosol and nucleus; used to study familial hyperlipidemia; biomarker of hepatocellular carcinoma; orthologous to human RGN (regucalcin); PARTICIPATES IN ascorbate and aldarate metabolic pathway; pentose phosphate pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: gluconolactonase; GNL; Rc; Reguc; regucalcin (senescence marker protein-30); senescence marker protein 30; SMP-30
Orthologs:
Homo sapiens (human) : RGN (regucalcin)  HGNC  Alliance
Mus musculus (house mouse) : Rgn (regucalcin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgn (regucalcin)
Pan paniscus (bonobo/pygmy chimpanzee) : RGN (regucalcin)
Canis lupus familiaris (dog) : RGN (regucalcin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgn (regucalcin)
Sus scrofa (pig) : RGN (regucalcin)
more info ...
Is Marker For: Strains:   SD-Tg(CAG-Rgn)Slc  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X1,833,484 - 1,848,904 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X2,626,525 - 2,641,949 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X13,037,171 - 13,052,846NCBIRGSC3.4rn4RGSC3.4
CeleraX2,182,952 - 2,198,371 (-)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rgn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3560
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.