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Gene: Mapk10 (mitogen activated protein kinase 10) Rattus norvegicus
Symbol: Mapk10
Name: mitogen activated protein kinase 10
CRRD ID: 3663
Description: Exhibits ATP binding activity and JUN kinase activity. Involved in several processes, including JUN phosphorylation; cellular hyperosmotic response; and response to water deprivation. Localizes to neuron projection; nucleus; and perikaryon. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human MAPK10 (mitogen-activated protein kinase 10); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-Jun N-terminal kinase 3; Jnk3; MAP kinase 10; MAPK 10; mitogen-activated protein kinase 10; p54-beta; SAPb; SAPK-beta; SAPKC; Serk2; Stress activated protein kinase beta; stress-activated protein kinase JNK3
Homo sapiens (human) : MAPK10 (mitogen-activated protein kinase 10)  HGNC  Alliance
Mus musculus (house mouse) : Mapk10 (mitogen-activated protein kinase 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk10 (mitogen-activated protein kinase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK10 (mitogen-activated protein kinase 10)
Canis lupus familiaris (dog) : MAPK10 (mitogen-activated protein kinase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk10 (mitogen-activated protein kinase 10)
Sus scrofa (pig) : MAPK10 (mitogen-activated protein kinase 10)
Chlorocebus sabaeus (African green monkey) : MAPK10 (mitogen-activated protein kinase 10)
Heterocephalus glaber (naked mole-rat) : Mapk10 (mitogen-activated protein kinase 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0148,079,955 - 8,371,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,080,275 - 8,368,254 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,053,697 - 8,344,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,719,595 - 8,010,694 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1147,719,594 - 8,010,694 (+)NCBI
Celera146,636,411 - 6,919,118 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mapk10
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3663
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.