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Gene: Srsf5 (serine and arginine rich splicing factor 5) Rattus norvegicus
Symbol: Srsf5
Name: serine and arginine rich splicing factor 5
CRRD ID: 3664
Description: Exhibits RNA binding activity and protein kinase B binding activity. Involved in several processes, including cellular response to insulin stimulus; liver regeneration; and positive regulation of RNA splicing. Localizes to nucleus. Orthologous to human SRSF5 (serine and arginine rich splicing factor 5); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 3-chloropropane-1,2-diol; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: delayed-early protein HRS; HRS; insulin-induced growth response protein CL-4; pre-mRNA-splicing factor SRP40; serine/arginine-rich splicing factor 5; Sfrs5; splicing factor arginine/serine-rich 5 (SRp40 HRS); splicing factor, arginine/serine-rich 5; splicing factor, arginine/serine-rich 5 (SRp40, HRS); SRp40
Homo sapiens (human) : SRSF5 (serine and arginine rich splicing factor 5)  HGNC  Alliance
Mus musculus (house mouse) : Srsf5 (serine and arginine-rich splicing factor 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf5 (serine and arginine rich splicing factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF5 (serine and arginine rich splicing factor 5)
Canis lupus familiaris (dog) : SRSF5 (serine and arginine rich splicing factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf5 (serine and arginine rich splicing factor 5)
Sus scrofa (pig) : SRSF5 (serine and arginine rich splicing factor 5)
Chlorocebus sabaeus (African green monkey) : SRSF5 (serine and arginine rich splicing factor 5)
Heterocephalus glaber (naked mole-rat) : Srsf5 (serine and arginine rich splicing factor 5)
more info ...
Related Pseudogenes: LOC107305674  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: Due to a potential assembly artifact, Rattus norvegicus Annotation Release 105 annotates the 5' end of this gene on chromosome 6 (NW_007905843.1) and the 3' end on chromosome 17 (NW_007906018.1) on Rnor_6.0. The correct location of this gene is on chromosome 6. [04 Mar 2016]; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06104,611,026 - 104,640,033 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6104,611,026 - 104,615,302 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06112,776,230 - 112,805,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01721,149,626 - 21,149,932 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46104,728,286 - 104,732,982 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16104,731,761 - 104,736,439 (+)NCBI
Celera698,461,136 - 98,465,890 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Srsf5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3664
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.