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Gene: Sftpa1 (surfactant protein A1) Rattus norvegicus
Symbol: Sftpa1
Name: surfactant protein A1
Description: Predicted to have monosaccharide binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to nitric oxide; and response to vitamin A. Localizes to extracellular space; multivesicular body; and rough endoplasmic reticulum. Biomarker of asthma; bacterial pneumonia; lung disease; newborn respiratory distress syndrome; and obesity. Human ortholog(s) of this gene implicated in lung disease (multiple) and respiratory syncytial virus infectious disease. Orthologous to several human genes including SFTPA1 (surfactant protein A1); PARTICIPATES IN forkhead class A signaling pathway; phagocytosis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC100364823; LOC102557073; MGC105453; PSAP; PSP-A; pulmonary surfactant-associated protein A; pulmonary surfactant-associated protein A-like; Sftp1; Sftpa; Sftpl; SP-A; surfactant associated protein A; surfactant, pulmonary-associated protein A1; Surfactant-associated protein 1 (pulmonary surfactant protein SP-A); Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01618,716,019 - 18,719,404 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1618,716,019 - 18,719,403 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01618,585,631 - 18,589,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,570,887 - 17,574,389 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1617,235,343 - 17,236,847 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sftpa1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3665
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.