Gene: Sftpd (surfactant protein D) Rattus norvegicus
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Symbol: Sftpd
Name: surfactant protein D
Description: Exhibits identical protein binding activity, lipopolysaccharide binding activity, and monosaccharide binding activity; involved in several processes, including negative regulation of T cell proliferation, negative regulation of interleukin-2 production, and regulation of phagocytosis; localizes to the extracellular space, multivesicular body, and rough endoplasmic reticulum; biomarker of asthma, bacterial pneumonia, chronic obstructive pulmonary disease, lung disease, and newborn respiratory distress syndrome; orthologous to human SFTPD (surfactant protein D); PARTICIPATES IN surfactant homeostasis pathway; forkhead class A signaling pathway; phagocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CP4; lung surfactant protein D; PSP-D; pulmonary surfactant protein D; pulmonary surfactant-associated protein D; SP-D; SPD; surfactant associated protein D; surfactant pulmonary-associated protein D; surfactant, pulmonary-associated protein D
Orthologs:
Homo sapiens (human) : SFTPD (surfactant protein D)  HGNC  Alliance
Mus musculus (house mouse) : Sftpd (surfactant associated protein D)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sftpd (surfactant protein D)
Pan paniscus (bonobo/pygmy chimpanzee) : SFTPD (surfactant protein D)
Canis lupus familiaris (dog) : SFTPD (surfactant protein D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sftpd (surfactant protein D)
Sus scrofa (pig) : SFTPD (surfactant protein D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01618,753,535 - 18,766,100 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01618,621,441 - 18,633,581 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1617,272,045 - 17,284,082 (-)NCBICelera
Cytogenetic Map16p14NCBI
RH 3.4 Map16167.0RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sftpd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3667
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.