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Gene: Slc14a2 (solute carrier family 14 member 2) Rattus norvegicus
Symbol: Slc14a2
Name: solute carrier family 14 member 2
CRRD ID: 3689
Description: Exhibits urea transmembrane transporter activity. Involved in response to water deprivation and urea transport. Predicted to localize to apical plasma membrane and integral component of membrane. Orthologous to human SLC14A2 (solute carrier family 14 member 2); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH (R)-noradrenaline; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: plasma membrane urea transporter; Slc14a1_v3; Slc14a1_v4; Slc14a2_v4; Slc14a2T; solute carrier family 14 (urea transporter), member 2; solute carrier family 14 (urea transporter), member 2, variant 4; solute carrier family 14 (urea transporter), member 2T; solute carrier family 14, member 2; testName; testSymbol; urea transport protein; Urea transporter; urea transporter 2; urea transporter UT-A2c; urea transporter UT-A2d; urea transporter, kidney; UrT1-C; UrT1-D; UT-A1; UT-A2; UT-A4; UTA3
Homo sapiens (human) : SLC14A2 (solute carrier family 14 member 2)  HGNC  Alliance
Mus musculus (house mouse) : Slc14a2 (solute carrier family 14 (urea transporter), member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc14a2 (solute carrier family 14 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC14A2 (solute carrier family 14 member 2)
Canis lupus familiaris (dog) : SLC14A2 (solute carrier family 14 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc14a2 (solute carrier family 14 member 2)
Sus scrofa (pig) : SLC14A2 (solute carrier family 14 member 2)
Chlorocebus sabaeus (African green monkey) : SLC14A2 (solute carrier family 14 member 2)
Heterocephalus glaber (naked mole-rat) : Slc14a2 (solute carrier family 14 member 2)
more info ...
Allele / Splice: Slc14a2_v1   Slc14a2_v2   Slc14a2_v3  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01874,508,070 - 74,941,389 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1874,546,220 - 74,688,551 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1874,508,069 - 74,542,077 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01874,185,426 - 74,617,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41875,071,416 - 75,499,738 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11875,144,693 - 75,325,630 (-)NCBI
Celera1870,129,421 - 70,555,892 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc14a2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3689
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.