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Gene: Slc22a5 (solute carrier family 22 member 5) Rattus norvegicus
Symbol: Slc22a5
Name: solute carrier family 22 member 5
Description: Exhibits carnitine transmembrane transporter activity. Involved in carnitine transport. Localizes to the basolateral plasma membrane. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5); INTERACTS WITH (+)-schisandrin B; (R)-carnitine; 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: CT1; high-affinity carnitine transporter; high-affinity sodium-dependent carnitine cotransporter; integral membrane transport protein; OCTN2; organic cation/carnitine transporter; organic cation/carnitine transporter 2; solute carrier family 22 (organic cation transporter) member 5; solute carrier family 22 (organic cation transporter), member 5; solute carrier family 22 (organic cation/carnitine transporter), member 5; solute carrier family 22, member 5; UST2r
Homo sapiens (human) : SLC22A5 (solute carrier family 22 member 5)  HGNC  Alliance
Mus musculus (house mouse) : Slc22a5 (solute carrier family 22 (organic cation transporter), member 5)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A5 (solute carrier family 22 member 5)
Canis lupus familiaris (dog) : SLC22A5 (solute carrier family 22 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a5 (solute carrier family 22 member 5)
Sus scrofa (pig) : SLC22A5 (solute carrier family 22 member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01039,201,101 - 39,228,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01038,982,882 - 39,009,871 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,311,729 - 39,338,718 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,325,353 - 39,352,341 (-)NCBI
Celera1037,351,299 - 37,378,255 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc22a5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3702
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.