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Gene: Slc34a1 (solute carrier family 34 member 1) Rattus norvegicus
Symbol: Slc34a1
Name: solute carrier family 34 member 1
Description: Exhibits PDZ domain binding activity and identical protein binding activity. Involved in several processes, including ion transmembrane transport; phosphate ion transport; and regulation of phosphate transport. Localizes to several cellular components, including apical plasma membrane; brush border membrane; and membrane raft. Biomarker of autosomal dominant polycystic kidney disease; chronic kidney disease (multiple); hyperthyroidism; hypophosphatemia; and hypothyroidism. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome; chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis. Orthologous to human SLC34A1 (solute carrier family 34 member 1); PARTICIPATES IN phosphate transport pathway; INTERACTS WITH ammonium chloride; bisphenol A; buspirone.
Type: protein-coding
Also known as: na(+)-dependent phosphate cotransporter 2A; na(+)/Pi cotransporter 2A; NaPi-2; naPi-2a; NAPI2A; Npt2; Slc17a2; sodium-dependent phosphate transport protein 2A; sodium-phosphate co-transporter type II; sodium-phosphate transport protein 2A; sodium/phosphate cotransporter 2A; solute carrier family 17 (sodium/hydrogen exchanger) member 2; solute carrier family 34 (sodium phosphate) member 1; Solute carrier family 34 (sodium phosphate), member 1; solute carrier family 34 (type II sodium/phosphate cotransporter), member 1; solute carrier family 34, member 1
Homo sapiens (human) : SLC34A1 (solute carrier family 34 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc34a1 (solute carrier family 34 (sodium phosphate), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc34a1 (solute carrier family 34 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC34A1 (solute carrier family 34 member 1)
Canis lupus familiaris (dog) : SLC34A1 (solute carrier family 34 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc34a1 (solute carrier family 34 member 1)
Sus scrofa (pig) : SLC34A1 (solute carrier family 34 member 1)
Chlorocebus sabaeus (African green monkey) : SLC34A1 (solute carrier family 34 member 1)
Heterocephalus glaber (naked mole-rat) : Slc34a1 (solute carrier family 34 member 1)
more info ...
Allele / Splice: Slc34a1em1Mcwi  
Genetic Models: SS-Slc34a1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0179,747,766 - 9,762,739 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,747,752 - 9,762,813 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,856,946 - 11,872,100 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,262,929 - 15,277,902 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,262,928 - 15,277,902 (-)NCBI
Celera179,297,383 - 9,312,355 (-)NCBICelera
Cytogenetic Map17p14NCBI
RH 3.4 Map1781.4RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc34a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3708
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.