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Gene: Slc4a1 (solute carrier family 4 member 1 (Diego blood group)) Rattus norvegicus
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Symbol: Slc4a1
Name: solute carrier family 4 member 1 (Diego blood group)
Description: Exhibits actin binding activity; enzyme binding activity; and protein C-terminus binding activity. Involved in several processes, including positive regulation of T cell proliferation; response to alkaline pH; and response to carbon dioxide. Localizes to several cellular components, including the Z disc; basolateral plasma membrane; and intercalated disc. Biomarker of iron deficiency anemia; metabolic acidosis; and renal tubular acidosis. Human ortholog(s) of this gene implicated in congenital hemolytic anemia; hereditary spherocytosis; hereditary spherocytosis type 4; malaria; and renal tubular acidosis. Orthologous to human SLC4A1 (solute carrier family 4 member 1 (Diego blood group)); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AE 1; anion exchange protein 1; anion exchanger 1; band 3 anion transport protein; MGC93554; solute carrier family 4 (anion exchanger), member 1; solute carrier family 4 member 1; Solute carrier family 4 member 1 anion exchange protein 1 (kidney band 3); solute carrier family 4, member 1; Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3)
Orthologs:
Is Marker For: QTLs:   BpQTLcluster1   BpQTLcluster9  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01090,296,144 - 90,312,401 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1090,296,141 - 90,312,386 (-)Ensembl
Rnor_5.01090,084,734 - 90,101,181 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,454,824 - 91,471,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11091,470,679 - 91,479,502 (-)NCBI
Celera1086,018,849 - 86,032,669 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc4a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3710
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.