Gene: Slc8a1 (solute carrier family 8 member A1) Rattus norvegicus
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Symbol: Slc8a1
Name: solute carrier family 8 member A1
Description: Exhibits calcium:sodium antiporter activity and ion antiporter activity involved in regulation of postsynaptic membrane potential; involved in several processes, including cation transport, regulation of heart contraction, and response to purine-containing compound; localizes to several cellular components, including the T-tubule, intracellular organelle, and neuron projection; used to study brain ischemia; biomarker of brain ischemia, congestive heart failure, hypertension, and status epilepticus; orthologous to human SLC8A1 (solute carrier family 8 member A1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (R)-noradrenaline; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: na(+)/Ca(2+)-exchange protein 1; Na-Ca exchanger; Ncx; Ncx1; sodium/calcium exchanger 1; solute carrier family 8 (sodium/calcium exchanger) member 1; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8, member 1
Orthologs:
Homo sapiens (human) : SLC8A1 (solute carrier family 8 member A1)  HGNC  Alliance
Mus musculus (house mouse) : Slc8a1 (solute carrier family 8 (sodium/calcium exchanger), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc8a1 (solute carrier family 8 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC8A1 (solute carrier family 8 member A1)
Canis lupus familiaris (dog) : SLC8A1 (solute carrier family 8 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc8a1 (solute carrier family 8 member A1)
Sus scrofa (pig) : SLC8A1 (solute carrier family 8 member A1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.064,244,076 - 4,564,262 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.064,208,126 - 4,495,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.464,421,046 - 4,691,716 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.164,421,045 - 4,691,719 (-)NCBI
Celera612,962,979 - 13,227,191 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

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